Are you ready to unlock the secret to a timeless glow?

We're all familiar with the saying, "beauty comes from within," and today, we're diving deep into the science behind this by highlighting Beauty Formula’s ingredients. We are going to explore the essence of true beauty which blooms naturally from within, nurtured by the right nutrients, meticulously curated in our best-selling Beauty Formula.

The journey to luminous skin, luscious hair, and strong nails isn't just about external skincare or the latest cosmetic product. It's about giving your body the nutritional building blocks it needs to regenerate, rejuvenate, and glow from the inside out. Our award-winning Beauty Formula has been crafted with this philosophy at its heart, with ingredients chosen for their scientifically validated benefits. Not only do Beauty Formula ingredients support your hair, skin, and nails, it provides total body support from hormones to digestion, addressing the underlying causes of problem skin, whilst supplementing your body with everything it needs to glow.

In this blog, we're going to take you behind the scenes, unveiling the potent ingredients in Beauty Formula and its transformative benefits. We'll delve into the wonders of botanical extracts, the power of proteins and amino acids, the pivotal role of vitamins, and the innovative delivery system that ensures your body absorbs these nutrients efficiently.

Whether you're a skincare enthusiast, a wellness devotee, or someone just embarking on a beauty journey, this blog will offer insights into the harmony between nutrition and beauty. We aim to empower you with knowledge so you can make informed decisions about your beauty regimen and understand why Beauty Formula has become a firm favourite amongst celebrities alike. So, get ready to nourish your inner goddess for that Equi glow!

The Science of Beauty: Unveiling the Active Ingredients in Beauty Formula

Beauty Formula is a multifaceted approach to beauty and wellness, which understands that radiant skin, strong nails, and lustrous hair are outward manifestations of inner health. Rooted in rigorous research, this unique blend amalgamates the most effective nutritional compounds, specifically chosen to address an array of skin concerns, and ensure the body's vitality. Firstly, we recognise that optimal beauty starts with balanced hormones. Hormonal fluctuations can cause havoc on your skin, leading to issues like acne, dryness, and premature ageing. Beauty Formula incorporates female-specific essential nutrients that support hormone balance and minimise these undesirable effects, fostering a clear and vibrant complexion. Simultaneously, it supports collagen production, a protein responsible for providing structure to your skin and strengthening your hair and nails. As we age, natural collagen production decreases, which may lead to wrinkles and brittle nails. By replenishing these collagen levels, Beauty Formula helps maintain your skin's elasticity, and enhance your hair and nail strength. What’s more, studies have shown that oral collagen peptide supplements could increase skin elasticity and hydration, leading to healthier, more youthful-looking skin (1).

Hydration is another crucial element for maintaining supple and radiant skin. With ingredients known for their hydrating properties, Beauty Formula helps to retain moisture within the skin, combating dryness, and promoting a youthful glow. For example, hyaluronic acid, is known for its capacity to retain large amounts of water. One study found that dietary hyaluronic acid could significantly improve skin hydration (2). Good skin also heavily relies on a healthy digestive system, as gut health and skin health are intricately connected. Studies highlight the intricate connection between gut health and skin health, emphasising that a healthy gut can lead to improved skin conditions (3). Beauty Formula includes components that support your digestive health, contributing to the overall wellness of your body and subsequently, improving your skin's appearance. Therefore, its benefits extend beyond the skin too. By supporting essential body functions, from hormone regulation to digestion, we strive to address the root causes of skin concerns. After all, beauty isn't merely about how we look on the outside, but how well our body functions on the inside. Through this holistic approach, Beauty Formula provides the body with the nutrients it needs not only to shine on the outside but also to thrive on the inside!

Beauty Formula’s Star Ingredients

Collagen-stimulating Antioxidants: GlowCutis® Blend

At Beauty Formula’s core is EQUI’s proprietary GlowCutis® blend, a collagen-stimulating, antioxidant powerhouse to nourish skin, hair, and nails. Containing hyaluronic acid, type 1 marine collagen peptides, zinc, vitamin C, pine bark extract, resveratrol, and silica, which work together to support every stage of the skin cell cycle, strengthening and helping to counteract premature skin ageing. At the heart of the GlowCutis® blend are Type 1 marine collagen peptides, which play a crucial role in the restoration and elasticity of the skin. Type 1 collagen is the most abundant collagen in the human body, forming a crucial part of our skin, hair, and nails. Supplementation with marine collagen peptides has been scientifically proven to improve skin elasticity, reduce wrinkles, and increase dermal collagen density (4). Another vital component is hyaluronic acid, a naturally occurring substance in the body that retains water to keep your tissues well lubricated. When it comes to skin health, hyaluronic acid's primary function is to retain water to keep your skin hydrated and plump, which helps to smooth fine lines and wrinkles (5). Zinc is a powerful trace element that aids in the production of proteins and DNA in the skin cells, assisting in the skin healing process, and possesses antioxidant properties to combat oxidative stress that leads to skin aging (6). Vitamin C from acerola cherry, resveratrol, and pine bark extract are potent antioxidants that help neutralise harmful free radicals, thereby protecting the skin cells from damage. Not only does vitamin C promote collagen synthesis (7), but research also shows that both resveratrol (8) and pine bark extract (9) can inhibit signs of ageing and enhance skin health. Lastly, silica, an essential mineral, helps to strengthen hair, skin, and nails, and has been shown to increase collagen production in the body (10). Every single ingredient in the GlowCutis® blend contributes to a different stage of the skin cell cycle, ensuring your skin, hair, and nails are continually nourished, protected, and rejuvenated.

Hormone Balancing Nutrients: Adaptogenic Herbs, & Vitamin B6

Beauty Formula includes a hormone balancing blend of adaptogenic herbs including schisandra and reishi mushroom extract. Add to the mix the vitamin B6, and you have a cocktail that actively works to support your hormonal health. Starting with schisandra, this adaptogenic herb has been used for centuries in traditional Chinese medicine for its plethora of health benefits. Schisandra helps the body resist stressors of all kinds, not just physical, but also chemical and biological. Research indicates that it enhances the body's resistance to stress and disease and improves physical performance and endurance. Studies also show that schisandra may positively impact hormonal health, particularly supporting the adrenal gland function and the body's stress response (11). Reishi mushroom extract is known for its immune-enhancing and anti-inflammatory effects. But beyond that, research has shown that it can also help to modulate the hormonal system. Studies show us that reishi mushroom extracts had an anti-androgenic effect, essentially helping to balance hormone levels (12). Finally, vitamin B6, which plays an integral role in hormone regulation, is particularly important in the synthesis of key neurotransmitters that regulate mood, such as serotonin and dopamine. Furthermore, vitamin B6 aids in the production of red blood cells, which helps transport oxygen throughout the body, contributing to hormone balance (13). These hormone-balancing nutrients work together to support and stabilise your body, providing a foundation for holistic health that shines from within.

Energy Support: B-vitamins, Magnesium & Iron

B-vitamins, magnesium, and iron are key players in the body’s energy support system, working together to combat tiredness and fatigue. B-vitamins serve as vital co-enzymes in cellular energy production, with vitamins B1, B2, B3, B5, B6, and B12 playing specific roles in the complex biochemical machinery that converts food into energy (14). A deficiency in these nutrients can lead to reduced energy levels and increased fatigue. Meanwhile, magnesium is involved in over 300 enzyme reactions in the body, including those responsible for energy production. According to studies, magnesium plays a pivotal role in the body's energy balance, with deficiency linked to higher levels of perceived exertion, muscle fatigue, and tiredness (15). Finally, iron is crucial for the production of haemoglobin, a protein in your red blood cells that carries oxygen around your body. An iron deficiency can result in lower oxygen delivery to your cells, leading to tiredness and fatigue. These essential nutrients, when combined, offer a powerful tool in fighting fatigue and supporting your energy levels. Ensuring adequate intake can be key to keeping you feeling vibrant and ready to take on anything.

Skin Cell Health: Biotin, Selenium & Niacin

A healthy complexion is often a reflection of well-nourished skin cells. Key nutrients that support this vital aspect through Beauty Formula are biotin, selenium, and niacin. They work at the cellular level, promoting the health of skin cells and contribute to radiant, resilient skin. Biotin, also known as vitamin B7, is fundamental to maintaining the health of our skin, hair, and nails. It aids in the production of fatty acids within the skin, contributing to a healthy skin barrier which helps to maintain hydration and protect against irritants (16). It also plays a role in the growth and repair of skin cells. Selenium is a potent antioxidant that plays a crucial role in preserving the health of your skin. One study reported that selenium protects skin cells from oxidative damage, promoting a healthy and youthful complexion (17). Niacin, or vitamin B3, is another skin-loving nutrient. It helps to enhance the skin's barrier function, improve skin texture, and retain moisture (18). Its anti-inflammatory properties are also beneficial in managing skin conditions like acne and rosacea. Together, biotin, selenium, and niacin are three vital ingredients in the recipe for beautiful, healthy skin. Ensuring these nutrients were included in Beauty Formula was essential to help support the maintenance of healthy skin cells, contributing to an enviable Equi glow!

Supports Gut Integrity: Glutamine

The gut plays a pivotal role in overall health, including skin health. One key nutrient that supports gut health is glutamine. Glutamine is an amino acid that fuels the cells of the intestines, supports the function of the immune system, and helps maintain the integrity of the intestinal wall, reducing the risk of something known as 'leaky gut'. The cells in the gut lining turn over rapidly, and their growth and repair are heavily dependent on the availability of glutamine. One study found that glutamine supplementation could support the growth of intestinal cells and maintain the integrity of the gut wall, helping to prevent the occurrence of 'leaky gut' (19). Moreover, glutamine also plays an essential role in the immune system, particularly in the gut, where the bulk of the immune system resides. Studies show us that glutamine can help fuel the immune cells in the gut, promoting their function and enhancing the body's defence mechanisms (20). Finally, glutamine is a critical nutrient in managing inflammation in the gut (21). Gut health became a big focus when formulating Beauty Formula because we understand that the skin reflects what’s going on in the gut. Since glutamine is a powerful nutrient that supports gut health, from maintaining the integrity of the gut wall to bolstering the immune system and controlling inflammation, it was vital to include this in Beauty Formula.

Nurturing the Microbiome: 1.5 Billion Vegan Probiotics (Lactobacillus sporogenes, Bifidobacterium bifidum, Bifidobacterium longum)

Probiotics, often hailed as 'good bacteria', are an integral part of digestive and overall health. The strains included in Beauty Formula, which are Lactobacillus sporogenes, Bifidobacterium bifidum, and Bifidobacterium longum, have been scientifically shown to provide multiple health benefits. Digestive health is significantly influenced by the balance of microorganisms in our gut. L. sporogenes, a spore-forming probiotic, has been shown to promote a healthier gut environment. This strain has been reported to aid in diarrhoea prevention, improve digestion, and enhance the immune response (22). B. bifidum and B. longum, known as Bifidobacteria, are some of the most common commensal (‘good’) bacteria found in the gut. These strains contribute to overall digestive health, aiding nutrient absorption and supporting the body's defence against harmful bacteria (23). Emerging research is starting to uncover a link between probiotics and skin health. An exciting study suggests that oral probiotics could regulate the release of inflammatory cytokines within the skin, making probiotics a potential aid for dermatological conditions such as acne and rosacea (24). Furthermore, studies suggest that certain probiotics might help manage bloating and water retention, common concerns for many women (25). By promoting a balanced gut, probiotics could influence fluid regulation in the body, thereby reducing feelings of bloating. The integration of these probiotic strains in Beauty Formula can support a holistic approach to beauty, contributing not just to digestive health, but also skin health.

Aids Digestion & Absorption of Nutrients: Digestive Enzymes Bromelain & Papain

Digestive enzymes like bromelain and papain play a crucial role in our health, influencing everything from our digestion to the vitality of our skin. Bromelain, an enzyme found in the pineapple plant, has long been utilised in traditional medicine and has gained scientific recognition for its digestive and anti-inflammatory benefits. Studies show bromelain aids in the digestion of proteins, reducing symptoms of indigestion like bloating, gas, and stomach discomfort (26). Furthermore, due to its anti-inflammatory and analgesic properties, bromelain has shown potential in the management of skin conditions, including wound healing (27). Similarly, papain, a proteolytic enzyme derived from the papaya fruit, has notable benefits for digestive and skin health. It eases digestion by helping break down proteins in the diet (28) and remember, you are what you absorb, meaning digestion and absorption are key! Both bromelain and papain are powerful plant-derived enzymes that bolster digestive health, indirectly promoting healthier skin. Their protein-digesting and anti-inflammatory properties lend support to the intricate relationship between digestion and skin health, reinforcing the belief that beauty truly does start from within and with Beauty Formula! 

Anti-inflammatory Support: Turmeric Extract

Turmeric, a golden spice revered in traditional medicine for its health-enhancing properties, is now gaining attention in the beauty community, particularly for its active compound, curcumin. The therapeutic potential of curcumin extends to a range of health areas, but its anti-inflammatory capabilities and its role in gut health are especially compelling. Inflammation is a natural part of the body's defence system, but when it becomes chronic, it can lead to various health issues, including skin problems. Curcumin in turmeric has been shown to exert potent anti-inflammatory effects. It achieves this by inhibiting inflammatory pathways, reducing the production of pro-inflammatory mediators (29). This helps in alleviating swollen and sore areas and can be beneficial for skin conditions linked to inflammation. Beyond its anti-inflammatory properties, curcumin has shown promise in enhancing gut health. Recent research shows it can positively modulate gut microbiota, supporting a healthy gut environment (30). A healthy gut is linked with overall health, including clear, radiant skin. This connection, known as the gut-skin axis, highlights how gut health can reflect in our skin (31). Therefore, the inclusion of turmeric extract in Beauty Formula not only helps to curb inflammation but also supports gut health, providing a holistic approach to beauty. Read more about the gut-skin axis in our recent blog.

Immune Support: Vitamins D, Zinc and Selenium

A radiant complexion and luscious locks aren't merely about external beauty practices, but are also closely tied to our internal health, particularly our immune system. In Beauty Formula, we've ensured that your immune health is well-supported with the inclusion of Vitamins D, Zinc, and Selenium, nutrients fundamental to immune function. Vitamin D, often termed the "sunshine vitamin", is an indispensable player in immune regulation. It boosts the body's defences by enhancing the function of immune cells, including T cells and macrophages, that protect your body against pathogens (32). This is vital not just for general health, but also for maintaining healthy skin. Zinc, an essential trace element, is another immune-supporting powerhouse. Zinc deficiency is associated with impaired immune function, illustrating its crucial role in maintaining a robust immune response. It's involved in the growth and function of various immune cells such as neutrophils and killer cells. For the skin, zinc aids in the process of wound healing and plays a role in managing inflammatory response related to acne and other skin conditions. Selenium, another trace mineral, is well-regarded for its antioxidant properties and role in bolstering immunity. It aids in lowering oxidative stress in the body, which enhances immunity and helps reduce inflammation (33). In essence, by supporting your immune system with Vitamin D, Zinc, and Selenium, Beauty Formula serves as a comprehensive solution for internal health that reflects externally in your skin and hair health.

Promotes Detoxification: Methionine & Glutathione

Beauty Formula harnesses the powerful benefits of methionine and glutathione, key components that work synergistically to protect your body and skin from oxidative stress and promote detoxification. Methionine, an essential amino acid, plays a vital role in many cell functions. Importantly, it is a precursor to the antioxidant glutathione, which our bodies cannot produce without sufficient methionine. Methionine assists in the production of collagen, a protein that gives our skin elasticity and strength. Furthermore, Methionine also aids in the detoxification process of the liver, which indirectly benefits the skin by flushing toxins out of the body. Glutathione, often referred to as the "master antioxidant", is a tripeptide composed of three amino acids: cysteine, glutamate, and glycine. Glutathione protects cells from oxidative damage, which accelerates the ageing process and can lead to numerous health issues. Glutathione also recycles other antioxidants, making them more effective, and plays a significant role in immune function. Beauty Formula's unique combination of methionine and glutathione provides an integral boost to your body's defence system, detoxification processes, and overall skin health. 

Beauty Formula’s Delivery System Maximises Nutrient Uptake for Enhanced Beauty Benefits

A crucial aspect of Beauty Formula's effectiveness is its innovative delivery system that ensures optimal absorption and utilisation of nutrients in the body. After all, it's not just about what you consume but how well your body can use it that makes a real difference to your health and beauty. Our bodies operate in a complex biochemical environment, and simply ingesting a nutrient doesn't guarantee its effective use. This is why the delivery system of our supplement is as important as its ingredients. Beauty Formula employs a two-fold strategy: it provides active, highly bioavailable forms of nutrients and combines them in a way that supports their absorption and synergy. Scientific studies highlight that certain nutrients enhance the absorption of others. For instance, vitamin C has been shown to increase the absorption of collagen, two key ingredients in Beauty Formula (34). Moreover, Beauty Formula includes digestive enzymes such as bromelain and papain, which can help break down food and enhance nutrient absorption (35). It also contains probiotics, beneficial bacteria that can support the gut's health and further assist in nutrient uptake (36). In essence, Beauty Formula is designed to make the most out of every single nutrient it contains, working in harmony with the body's natural processes. It's this smart, science-backed approach that helps you see real results, from radiant skin to stronger hair and nails, and an overall sense of well-being.

Beauty Formula is meticulously designed to target the multifaceted aspects of beauty and wellness from within. It harnesses the power of nature and science to give you a clear, bright complexion, stronger hair and nails, and help you fight off hormonal breakouts and other skin issues. Not only this, but it helps with fine lines, dark circles, & anti-ageing and supports hormones & gut health. Have you read our recent Summer Skin Series where we touch on some of these topics?  Click HERE to read.

Celeb Endorsed: Billie Piper Approves!

Billie Piper, renowned actress and singer, has sung the praises of Beauty Formula. Billie stumbled upon Equi on Instagram, and what started as a tentative trial ahead of a significant filming project quickly turned into a beauty regimen staple. As an actress, Billie's face is her calling card, always in the limelight, scrutinised at all angles, and captured in high-definition detail. So, when she faced skin troubles, she knew she needed a solution, and not just a temporary one for her filming schedule, but a long-term remedy that would boost her confidence in life, beyond the camera lens. After incorporating Equi's Beauty Formula into her daily routine, Billie saw a marked improvement in her skin. It wasn't just a few less noticeable blemishes or temporary glow; it was a transformative change that she felt and saw every day. Her skin troubles were a thing of the past; she was now spot-free and had a radiant glow that was noticeable both on and off the camera. But the magic of Beauty Formula didn't just stop at her skin. She felt better overall, a testament to the holistic approach of our product, which works on not just your external appearance but your overall well-being from within. And for someone who has to juggle the demands of a high-pressure career with the ups and downs of everyday life, that's a priceless benefit. Billie's endorsement is a powerful testament to the effectiveness of Beauty Formula. A thank you from her is a reminder to us that our mission to provide effective, natural, and scientifically backed solutions for beauty and health is impacting lives, one radiant, confident smile at a time.

Billie Piper said:

“I came across Equi on Insta and started taking it ahead of filming a big project. I’d been experiencing troublesome skin which I wanted to fix, especially whilst spending every day in front of the camera, but also for life in general. Equi Beauty Formula quickly became a part of my daily routine, and I can honestly say it saved my skin during filming and has continued to do so. I now have complete confidence that I will be spot free, glowing…and feel pretty good too! I wanted to say a big thank you to Equi for this brilliant product.”

References

1. Borumand, M., et al., (2019). Daily consumption of the collagen supplement Pure Gold Collagen® reduces visible signs of aging. Clinical Interventions in Aging, 9, p.1747.

2. Pavicic, T., et al., (2011). Efficacy of Cream-Based Novel Formulations of Hyaluronic Acid of Different Molecular Weights in Anti-Wrinkle Treatment. Journal of Drugs in Dermatology, 10(9), pp.990-1000.

3. Salem, I., et al., (2018). The Gut Microbiome as a Major Regulator of the Gut-Skin Axis. Frontiers in Microbiology, 9, p.1459.

4. Inoue N., et al., (2016). Ingestion of Bioactive Collagen Hydrolysates Enhance Facial Skin Moisture and Elasticity and Reduce Facial Ageing Signs in a randomised double-blind placebo-controlled clinical study. Journal of the Science of Food and Agriculture, 96(12), pp.4077–4081.

5. Pavicic, T., et al., (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology, 10(9), pp.990-1000.

6. Rajagopalan, S., et al., (2013). Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses. PloS one, 8(5), e57544.

7. Pullar, J.M., et al., (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), p.866.

8. Buonocore, D., et al., (2015). Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebo-controlled, double-blind study. Clinical, Cosmetic and Investigational Dermatology, 8, p.417.

9. Grether-Beck, S., et al., (2012). French maritime pine bark extract (Pycnogenol®) effects on human skin: clinical and molecular evidence. Skin Pharmacology and Physiology, 25(2), pp.86-92.

10. Jugdaohsingh, R., et al., (2003). Silicon and bone health. The journal of nutrition, health & aging, 7(2), pp.99-110.

11. Szopa, A., Ekiert, R., & Ekiert, H. (2017). Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies. Phytochemistry Reviews, 16(2), pp. 195-218.

12. Chiu, H. F., et al. (2012). Triterpenoids and polysaccharide peptides-enriched Ganoderma lucidum: a randomized, double-blind placebo-controlled crossover study of its antioxidation and hepatoprotective efficacy in healthy volunteers. Pharmaceutical Biology, 50(6), pp. 696-703.

13. Hvas, A. M., Juul, S., Bech, P., & Nexø, E. (2004). Vitamin B6 level is associated with symptoms of depression. Psychotherapy and Psychosomatics, 73(6), pp. 340-343.

14. Kennedy, D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review. Nutrients, 8(2), p. 68.

15. Zhang, Y., Xun, P., Wang, R., Mao, L., & He, K. (2017). Can Magnesium Enhance Exercise Performance? Nutrients, 9(9), p. 946.

16. Zempleni, J., Wijeratne, S. S. K., & Hassan, Y. I. (2008). Biotin. BioFactors, 35(1), pp. 36-46.

17. Brigelius-Flohé, R., & Flohé, L. (2012). Selenium and redox signaling. Archives of biochemistry and biophysics, 525(2), pp. 145-149.

18. Chen, A. C., Damian, D. L., & Halliday, G. M. (2015). Oral and systemic photoprotection. Photodermatology, Photoimmunology & Photomedicine, 31(2), pp. 102-111.

19. Kaya, E., Karabeyoğlu, M., Ulusoy, S., Bilgiç, Y., Uğurluoğlu, C., & Yılmazlar, T. (2016). Glutamine-enriched enteral nutrition in abdominal surgery. Turkish Journal of Surgery, 32(3), p. 171.

20. Cruzat, V. F., Krause, M., & Newsholme, P. (2014). Amino acid supplementation and impact on immune function in the context of exercise. Journal of the International Society of Sports Nutrition, 11(1), p. 61.

21. Wang, B., Wu, G., Zhou, Z., Dai, Z., Sun, Y., Ji, Y., Li, W., Wang, W., Liu, C., Han, F., Wu, Z. (2015). Glutamine and intestinal barrier function. Amino Acids, 47(10), pp. 2143-2154.

22. Hun, L. (2009). Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS. Postgraduate Medicine, 121(2), pp. 119-124.

23. Tojo, R., Suárez, A., Clemente, M. G., de los Reyes-Gavilán, C. G., Margolles, A., Gueimonde, M., & Ruas-Madiedo, P. (2014). Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis. World Journal of Gastroenterology, 20(41), p. 15163.

24. Bowe, W. P., & Logan, A. C. (2011). Acne vulgaris, probiotics and the gut-brain-skin axis: from anecdote to translational medicine. Beneficial Microbes, 2(2), pp. 167-179.

25. Ng, Q. X., Peters, C., Ho, C. Y. X., Lim, D. Y., & Yeo, W. S. (2018). A meta-analysis of the use of probiotics to alleviate depressive symptoms. Journal of Affective Disorders, 228, pp. 13-19.

26. Roxas, M. (2008). The role of enzyme supplementation in digestive disorders. Alternative Medicine Review, 13(4), pp. 307-314.

27. Sampson, M., Fuller, C., & Slater, D. (2012). Bromelain for treating burns. The Cochrane Library.

28. Kaur, M., & Athar, M. (2011). Papain: a novel urine adulterant. Journal of Clinical Laboratory Analysis, 25(1), pp. 46-51.

29. Aggarwal, B.B., Sundaram, C., Malani, N., & Ichikawa, H. (2007). Curcumin: The Indian Solid Gold. Advances in Experimental Medicine and Biology, 595, pp. 1-75.

30. Peterson, C.T., Vaughn, A.R., Sharma, V., Chopra, D., Mills, P.J., Peterson, S.N., & Sivamani, R.K. (2018). Effects of Turmeric and Curcumin Dietary Supplementation on Human Gut Microbiota: A Double-Blind, Randomized, Placebo-Controlled Pilot Study. Journal of Evidence-Based Integrative Medicine, 23, pp. 1-8.

31. Salem, I., Ramser, A., Isham, N., & Ghannoum, M.A. (2018). The Gut Microbiome as a Major Regulator of the Gut-Skin Axis. Frontiers in Microbiology, 9, p. 1459.

32. Aranow, C. (2011). Vitamin D and the immune system. Journal of investigative medicine, 59(6), pp. 881-886.

33. Hoffmann, P. R., & Berry, M. J. (2008). The influence of selenium on immune responses. Molecular nutrition & food research, 52(11), pp. 1273-1280.

34. Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), p. 866.

35. Roxas, M. (2008). The Role of Enzyme Supplementation in Digestive Disorders. Alternative Medicine Review, 13(4), pp. 307–314.

36. Dimidi, E., Christodoulides, S., Scott, S. M., & Whelan, K. (2019). Mechanisms of Action of Probiotics and the Gastrointestinal Microbiota on Gut Motility and Constipation. Advances in Nutrition, 10(3), pp. 498–512.